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Cyclic adenosine 5’-monophosphate response element modulator α suppresses spleen tyrosine kinase expression in normal but not in SLE T cells

OBJECTIVE: T cells from patients with systemic lupus erythematosus (SLE) display increased amounts of spleen tyrosine kinase (SYK) which is involved in the aberrant CD3/T cell receptor-mediated signaling process and increased amounts of cAMP response element modulator (CREM) α which suppresses the p...

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Detalhes bibliográficos
Main Authors: Ghosh, Debjani, Kis-Toth, Katalin, Juang, Yuang-Taung, Tsokos, George C.
Formato: Artigo
Idioma:Inglês
Publicado em: 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3250560/
https://ncbi.nlm.nih.gov/pubmed/21953500
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/art.33375
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