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Inhibition of calcium/calmodulin-dependent protein kinase type IV results in suppression of autoimmunity and organ pathology in lupus-prone mice

OBJECTIVE: Systemic lupus erythematousus (SLE) is a chronic inflammatory disease associated with aberrant immune cell function. Treatment involves the use of indiscriminate immunosuppression with significant side effects. SLE T cells express high levels of calcium/calmodulin-dependent protein kinase...

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Main Authors: Ichinose, Kunihiro, Juang, Yuang-Taung, Crispín, José C., Kis-Toth, Katalin, Tsokos, George C.
格式: Artigo
語言:Inglês
出版: 2011
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC3030625/
https://ncbi.nlm.nih.gov/pubmed/20954187
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/art.30085
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