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Spleen tyrosine kinase inhibition in the treatment of autoimmune, allergic and autoinflammatory diseases

Spleen tyrosine kinase (Syk) is involved in the development of the adaptive immune system and has been recognized as being important in the function of additional cell types, including platelets, phagocytes, fibroblasts, and osteoclasts, and in the generation of the inflammasome. Preclinical studies...

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Autori principali: Pamuk, Omer N, Tsokos, George C
Natura: Artigo
Lingua:Inglês
Pubblicazione: BioMed Central 2010
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3046528/
https://ncbi.nlm.nih.gov/pubmed/21211067
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/ar3198
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