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Suppression of Skin and Kidney Disease by Inhibition of Spleen Tyrosine Kinase in Lupus-Prone Mice

OBJECTIVE: Spleen tyrosine kinase (Syk) is involved in membrane-mediated signaling in various cells, including immune cells. It is overexpressed in T cells from patients with systemic lupus erythematosus (SLE), and its inhibition has been shown to improve T cell function as well as to improve diseas...

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Detalhes bibliográficos
Main Authors: Deng, Guo-Min, Liu, Lena, Bahjat, Frances Rena, Pine, Polly R., Tsokos, George C.
Formato: Artigo
Idioma:Inglês
Publicado em: 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2902591/
https://ncbi.nlm.nih.gov/pubmed/20222110
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/art.27452
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