Mutations of complement lectin pathway genes MBL2 and MASP2 associated with placental malaria

BACKGROUND: Innate immunity plays a crucial role in the host defense against malaria including Plasmodium falciparum malaria in pregnancy, but the roles of the various underlying genes and mechanisms predisposing to the disease are poorly understood. METHODS: 98 single-nucletoide polymorphisms were...

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Détails bibliographiques
Auteurs principaux: Holmberg, Ville, Onkamo, Päivi, Lahtela, Elisa, Lahermo, Päivi, Bedu-Addo, George, Mockenhaupt, Frank P, Meri, Seppo
Format: Artigo
Langue:Inglês
Publié: BioMed Central 2012
Sujets:
Research
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3320545/
https://ncbi.nlm.nih.gov/pubmed/22380611
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1475-2875-11-61
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