Mutations of complement lectin pathway genes MBL2 and MASP2 associated with placental malaria

BACKGROUND: Innate immunity plays a crucial role in the host defense against malaria including Plasmodium falciparum malaria in pregnancy, but the roles of the various underlying genes and mechanisms predisposing to the disease are poorly understood. METHODS: 98 single-nucletoide polymorphisms were...

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Autors principals: Holmberg, Ville, Onkamo, Päivi, Lahtela, Elisa, Lahermo, Päivi, Bedu-Addo, George, Mockenhaupt, Frank P, Meri, Seppo
Format: Artigo
Idioma:Inglês
Publicat: BioMed Central 2012
Matèries:
Research
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3320545/
https://ncbi.nlm.nih.gov/pubmed/22380611
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1475-2875-11-61
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