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Conditional Inactivation of Noggin in the Postnatal Skeleton Causes Osteopenia

Noggin is an antagonist of bone morphogenetic proteins (BMP), and its overexpression causes suppressed osteoblastogenesis and osteopenia. Global inactivation of Noggin results in severe developmental defects and prenatal lethality, but the consequences of the conditional inactivation of Noggin on th...

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Detalhes bibliográficos
Main Authors: Canalis, Ernesto, Brunet, Lisa J., Parker, Kristen, Zanotti, Stefano
Formato: Artigo
Idioma:Inglês
Publicado em: Endocrine Society 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3320258/
https://ncbi.nlm.nih.gov/pubmed/22334719
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1210/en.2011-1604
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