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GREMLIN1 IS REQUIRED FOR SKELETAL DEVELOPMENT AND POSTNATAL SKELETAL HOMEOSTASIS

Gremlin is an antagonist of bone morphogenetic proteins, and its overexpression causes suppressed osteoblastogenesis and osteopenia. Inactivation of Grem1 results in severe developmental defects, but the consequences of the global inactivation of Grem1 on the postnatal skeleton are not known. To stu...

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Detalhes bibliográficos
Main Authors: Canalis, Ernesto, Parker, Kristen, Zanotti, Stefano
Formato: Artigo
Idioma:Inglês
Publicado em: 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3132213/
https://ncbi.nlm.nih.gov/pubmed/21412775
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/jcp.22730
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