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GREMLIN1 IS REQUIRED FOR SKELETAL DEVELOPMENT AND POSTNATAL SKELETAL HOMEOSTASIS

Gremlin is an antagonist of bone morphogenetic proteins, and its overexpression causes suppressed osteoblastogenesis and osteopenia. Inactivation of Grem1 results in severe developmental defects, but the consequences of the global inactivation of Grem1 on the postnatal skeleton are not known. To stu...

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Bibliografske podrobnosti
Main Authors: Canalis, Ernesto, Parker, Kristen, Zanotti, Stefano
Format: Artigo
Jezik:Inglês
Izdano: 2012
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3132213/
https://ncbi.nlm.nih.gov/pubmed/21412775
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/jcp.22730
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