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Opiate-induced constipation related to activation of small intestine opioid μ2-receptors
AIM: To investigate the role of opioid μ-receptor subtype in opiate-induced constipation (OIC). METHODS: The effect of loperamide on intestinal transit was investigated in mice. Ileum strips were isolated from 12-wk-old male BALB/c mice for identification of isometric tension. The ileum strips were...
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| Autori principali: | , , |
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| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
Baishideng Publishing Group Co., Limited
2012
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3319967/ https://ncbi.nlm.nih.gov/pubmed/22493554 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3748/wjg.v18.i12.1391 |
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