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Opiate-induced constipation related to activation of small intestine opioid μ2-receptors

AIM: To investigate the role of opioid μ-receptor subtype in opiate-induced constipation (OIC). METHODS: The effect of loperamide on intestinal transit was investigated in mice. Ileum strips were isolated from 12-wk-old male BALB/c mice for identification of isometric tension. The ileum strips were...

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Hlavní autoři: Chen, Wency, Chung, Hsien-Hui, Cheng, Juei-Tang
Médium: Artigo
Jazyk:Inglês
Vydáno: Baishideng Publishing Group Co., Limited 2012
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3319967/
https://ncbi.nlm.nih.gov/pubmed/22493554
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3748/wjg.v18.i12.1391
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