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The role of covalent dimerization on the physical and chemical stability of the EC1 domain of human E-cadherin
The objective of this work was to evaluate the solution stability of the EC1 domain of E-cadherin under various conditions. The EC1 domain was incubated at various temperatures (4, 37, and 70 °C) and pH values (3.0, 7.0, and 9.0). At pH 9.0 and 37 or 70 °C, a significant loss of EC1 was observed due...
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| Главные авторы: | , , , , , , , |
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| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
2009
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3319692/ https://ncbi.nlm.nih.gov/pubmed/19199298 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/jps.21686 |
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