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Mitofusin2 Mutations Disrupt Axonal Mitochondrial Positioning and Promote Axon Degeneration

Alterations in mitochondrial dynamics (fission, fusion, and movement) are implicated in many neurodegenerative diseases, from rare genetic disorders such as Charcot-Marie-Tooth disease, to common conditions including Alzheimer's disease. However, the relationship between altered mitochondrial d...

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Bibliografiske detaljer
Main Authors: Misko, Albert L., Sasaki, Yo, Tuck, Elizabeth, Milbrandt, Jeffrey, Baloh, Robert H.
Format: Artigo
Sprog:Inglês
Udgivet: Society for Neuroscience 2012
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3319368/
https://ncbi.nlm.nih.gov/pubmed/22442078
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.6338-11.2012
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