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Transgenic Mice Expressing the Nmnat1 Protein Manifest Robust Delay in Axonal Degeneration In Vivo

Axonal degeneration is a key component of a variety of neurological diseases. Studies using wld(s) mutant mice have demonstrated that delaying axonal degeneration slows disease course and prolongs survival in neurodegenerative disease models. The Wld(s) protein is normally localized to the nucleus,...

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Detalhes bibliográficos
Main Authors: Sasaki, Yo, Vohra, Bhupinder P. S., Baloh, Robert H., Milbrandt, Jeffrey
Formato: Artigo
Idioma:Inglês
Publicado em: Society for Neuroscience 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2697066/
https://ncbi.nlm.nih.gov/pubmed/19458223
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.1429-09.2009
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