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Transgenic Mice Expressing the Nmnat1 Protein Manifest Robust Delay in Axonal Degeneration In Vivo

Axonal degeneration is a key component of a variety of neurological diseases. Studies using wld(s) mutant mice have demonstrated that delaying axonal degeneration slows disease course and prolongs survival in neurodegenerative disease models. The Wld(s) protein is normally localized to the nucleus,...

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Bibliographic Details
Main Authors: Sasaki, Yo, Vohra, Bhupinder P. S., Baloh, Robert H., Milbrandt, Jeffrey
Format: Artigo
Language:Inglês
Published: Society for Neuroscience 2009
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2697066/
https://ncbi.nlm.nih.gov/pubmed/19458223
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.1429-09.2009
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