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Mitofusin2 Mutations Disrupt Axonal Mitochondrial Positioning and Promote Axon Degeneration

Alterations in mitochondrial dynamics (fission, fusion, and movement) are implicated in many neurodegenerative diseases, from rare genetic disorders such as Charcot-Marie-Tooth disease, to common conditions including Alzheimer's disease. However, the relationship between altered mitochondrial d...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Misko, Albert L., Sasaki, Yo, Tuck, Elizabeth, Milbrandt, Jeffrey, Baloh, Robert H.
Format: Artigo
Sprache:Inglês
Veröffentlicht: Society for Neuroscience 2012
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3319368/
https://ncbi.nlm.nih.gov/pubmed/22442078
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.6338-11.2012
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