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Mitofusin 2 Is Necessary for Transport of Axonal Mitochondria and Interacts with the Miro/Milton Complex

Mitofusins (Mfn1 and Mfn2) are outer mitochondrial membrane proteins involved in regulating mitochondrial dynamics. Mutations in Mfn2 cause Charcot-Marie-Tooth disease (CMT) type 2A, an inherited disease characterized by degeneration of long peripheral axons, but the nature of this tissue selectivit...

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Detalhes bibliográficos
Main Authors: Misko, Albert, Jiang, Sirui, Wegorzewska, Iga, Milbrandt, Jeffrey, Baloh, Robert H.
Formato: Artigo
Idioma:Inglês
Publicado em: Society for Neuroscience 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2852190/
https://ncbi.nlm.nih.gov/pubmed/20335458
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.6248-09.2010
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