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Expression and purification of soluble porcine CTLA-4 in yeast Pichia pastoris

Co-stimulation blockade can be used to modulate the immune response for induction of organ transplantation tolerance, treatment of autoimmune disease as well as cancer treatment. Cytotoxic T-Lymphocyte Antigen-4 (CTLA-4), also known as CD152, is an important co-stimulatory molecule which serves as a...

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Autores principales: Peraino, Jaclyn, Zhang, Huiping, Hermanrud, Christina E., Li, Guoying, Sachs, David H., Huang, Christene A., Wang, Zhirui
Formato: Artigo
Lenguaje:Inglês
Publicado: 2012
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3319225/
https://ncbi.nlm.nih.gov/pubmed/22326797
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.pep.2012.01.012
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