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Structural requirements of bile acid transporters: C-3 and C-7 modifications of steroidal hydroxyl groups
The apical sodium dependent bile acid transporter (ASBT) and sodium-taurocholate cotransporting polypeptide (NTCP) are potential prodrug targets, but the structural requirements for these transporters are incompletely defined. The objective of this study was to evaluate the effect of C-3 and C-7 sub...
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| Hauptverfasser: | , |
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
2012
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3319149/ https://ncbi.nlm.nih.gov/pubmed/22387310 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ejps.2012.02.012 |
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