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Beta-arrestin-2 regulates cannabinoid CB(1) receptor signaling and adaptation in a CNS region-dependent manner

BACKGROUND: Cannabinoid CB(1) receptors (CB(1)R) mediate the effects of Δ(9)-tetrahydrocannabinol (THC), the psychoactive component in marijuana. Repeated THC administration produces tolerance and dependence, which limit therapeutic development. Moreover, THC produces motor and psychoactive side eff...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Nguyen, Peter T., Schmid, Cullen L., Raehal, Kirsten M., Selley, Dana E., Bohn, Laura M., Sim-Selley, Laura J.
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: 2012
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC3319102/
https://ncbi.nlm.nih.gov/pubmed/22264443
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.biopsych.2011.11.027
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