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Pharmaceutical inhibition of glycogen synthetase kinase-3β reduces multiple myeloma–induced bone disease in a novel murine plasmacytoma xenograft model

Multiple myeloma (MM) is a malignancy of plasma cells that accumulate in the bone marrow. MM is incurable with approximately 100 000 patients currently in the United States and 20 000 new cases diagnosed yearly. The malignancy causes displacement of hematopoiesis and formation of osteolytic bone les...

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Detalles Bibliográficos
Main Authors: Gunn, W. Grady, Krause, Ulf, Lee, Narae, Gregory, Carl A.
Formato: Artigo
Idioma:Inglês
Publicado: American Society of Hematology 2011
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3318776/
https://ncbi.nlm.nih.gov/pubmed/21123822
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2010-09-308171
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