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Pharmaceutical inhibition of glycogen synthetase kinase-3β reduces multiple myeloma–induced bone disease in a novel murine plasmacytoma xenograft model

Multiple myeloma (MM) is a malignancy of plasma cells that accumulate in the bone marrow. MM is incurable with approximately 100 000 patients currently in the United States and 20 000 new cases diagnosed yearly. The malignancy causes displacement of hematopoiesis and formation of osteolytic bone les...

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Detalhes bibliográficos
Main Authors: Gunn, W. Grady, Krause, Ulf, Lee, Narae, Gregory, Carl A.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society of Hematology 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3318776/
https://ncbi.nlm.nih.gov/pubmed/21123822
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2010-09-308171
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