Differential Use of CCR5 by HIV-1 Clinical Isolates Resistant to Small-Molecule CCR5 Antagonists

How HIV-1 resistant to small-molecule CCR5 antagonists uses the coreceptor for entry has been studied in a limited number of isolates. We characterized dependence on the N terminus (NT) and the second extracellular loop (ECL2) of CCR5 of three vicriviroc (VCV)-resistant clinical isolates broadly cro...

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Autores principales: Henrich, Timothy J., Lewine, Nicolas R. P., Lee, Sun-Hee, Rao, Suhas S. P., Berro, Reem, Gulick, Roy M., Moore, John P., Tsibris, Athe M. N., Kuritzkes, Daniel R.
Formato: Artigo
Lenguaje:Inglês
Publicado: American Society for Microbiology 2012
Materias:
Antiviral Agents
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3318367/
https://ncbi.nlm.nih.gov/pubmed/22252820
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.06061-11
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