Comparative oncology: ErbB-1 and ErbB-2 homologues in canine cancer are susceptible to cetuximab and trastuzumab targeting

To facilitate comparative oncology trials we compared the biological and molecular homologies of canine (dog; Canis lupus familiaris) and human tumor-associated antigens ErbB-1 and -2. Further, we investigated whether they could serve as targets for anti-ErbB-1 (cetuximab) and anti-ErbB-2 antibodies...

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Bibliografiska uppgifter
Huvudupphovsmän: Singer, Josef, Weichselbaumer, Marlene, Stockner, Thomas, Mechtcheriakova, Diana, Sobanov, Yury, Bajna, Erika, Wrba, Friedrich, Horvat, Reinhard, Thalhammer, Johann G., Willmann, Michael, Jensen-Jarolim, Erika
Materialtyp: Artigo
Språk:Inglês
Publicerad: Pergamon Press 2012
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Article
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC3318186/
https://ncbi.nlm.nih.gov/pubmed/22424313
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molimm.2012.01.002
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