Generation of a Canine Anti-EGFR (ErbB-1) Antibody for Passive Immunotherapy in Dog Cancer Patients

Passive immunotherapy with monoclonal antibodies represents a cornerstone of human anticancer therapies, but has not been established in veterinary medicine yet. As the tumor-associated antigen EGFR (ErbB-1) is highly conserved between humans and dogs, and considering the effectiveness of the anti-E...

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Auteurs principaux: Singer, Josef, Fazekas, Judit, Wang, Wei, Weichselbaumer, Marlene, Matz, Miroslawa, Mader, Alexander, Steinfellner, Willibald, Meitz, Sarah, Mechtcheriakova, Diana, Sobanov, Yuri, Willmann, Michael, Stockner, Thomas, Spillner, Edzard, Kunert, Renate, Jensen-Jarolim, Erika
Format: Artigo
Langue:Inglês
Publié: 2014
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Article
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4174294/
https://ncbi.nlm.nih.gov/pubmed/24755200
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1535-7163.MCT-13-0288
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