pH-Responsive Titratable Inotropic Performance of Histidine-Modified Cardiac Troponin I

Cardiac troponin I (cTnI) functions as the molecular switch of the thin filament. Studies have shown that a histidine button engineered into cTnI (cTnI A164H) specifically enhances inotropic function in the context of numerous pathophysiological challenges. To gain mechanistic insight into the basis...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Palpant, Nathan J., Houang, Evelyne M., Sham, Yuk Y., Metzger, Joseph M.
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: The Biophysical Society 2012
Gaiak:
Muscle, Motility and Motor Proteins
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC3318134/
https://ncbi.nlm.nih.gov/pubmed/22500757
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bpj.2012.01.024
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