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Molecular Determinants of Cardiac Myocyte Performance as Conferred by Isoform-Specific TnI Residues
Troponin I (TnI) is the molecular switch of the sarcomere. Cardiac myocytes express two isoforms of TnI during development. The fetal heart expresses the slow skeletal TnI (ssTnI) isoform and shortly after birth ssTnI is completely and irreversibly replaced by the adult cardiac TnI (cTnI) isoform. T...
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| Main Authors: | , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
The Biophysical Society
2014
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4052262/ https://ncbi.nlm.nih.gov/pubmed/24853739 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bpj.2014.04.017 |
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