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Single histidine-substituted cardiac troponin I confers protection from age-related systolic and diastolic dysfunction
AIMS: Contractile dysfunction associated with myocardial ischaemia is a significant cause of morbidity and mortality in the elderly. Strategies to protect the aged heart from ischaemia-mediated pump failure are needed. We hypothesized that troponin I-mediated augmentation of myofilament calcium sens...
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| Autors principals: | , , , , |
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| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
Oxford University Press
2008
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2567875/ https://ncbi.nlm.nih.gov/pubmed/18635554 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/cvr/cvn198 |
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