Single histidine-substituted cardiac troponin I confers protection from age-related systolic and diastolic dysfunction

AIMS: Contractile dysfunction associated with myocardial ischaemia is a significant cause of morbidity and mortality in the elderly. Strategies to protect the aged heart from ischaemia-mediated pump failure are needed. We hypothesized that troponin I-mediated augmentation of myofilament calcium sens...

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Hlavní autoři: Palpant, Nathan J., Day, Sharlene M., Herron, Todd J., Converso, Kimber L., Metzger, Joseph M.
Médium: Artigo
Jazyk:Inglês
Vydáno: Oxford University Press 2008
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Original Articles
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2567875/
https://ncbi.nlm.nih.gov/pubmed/18635554
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/cvr/cvn198
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