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Effect of cancer-associated mutations in the PlexinB1 gene

BACKGROUND: Semaphorins act as chemotactic cues for cell movement via their transmembrane receptors, plexins. Somatic missense mutations in the plexinB1 gene coupled with overexpression of the protein frequently occur in prostate tumours, indicating a role for plexinB1 in the pathogenesis of prostat...

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Autori principali: Zhou, Chun, Wong, Oscar Gee-Wan, Masters, John R, Williamson, Magali
Natura: Artigo
Lingua:Inglês
Pubblicazione: BioMed Central 2012
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3317836/
https://ncbi.nlm.nih.gov/pubmed/22404908
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1476-4598-11-11
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