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Effect of cancer-associated mutations in the PlexinB1 gene

BACKGROUND: Semaphorins act as chemotactic cues for cell movement via their transmembrane receptors, plexins. Somatic missense mutations in the plexinB1 gene coupled with overexpression of the protein frequently occur in prostate tumours, indicating a role for plexinB1 in the pathogenesis of prostat...

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Detalhes bibliográficos
Main Authors: Zhou, Chun, Wong, Oscar Gee-Wan, Masters, John R, Williamson, Magali
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3317836/
https://ncbi.nlm.nih.gov/pubmed/22404908
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1476-4598-11-11
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