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Effect of cancer-associated mutations in the PlexinB1 gene

BACKGROUND: Semaphorins act as chemotactic cues for cell movement via their transmembrane receptors, plexins. Somatic missense mutations in the plexinB1 gene coupled with overexpression of the protein frequently occur in prostate tumours, indicating a role for plexinB1 in the pathogenesis of prostat...

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Autors principals: Zhou, Chun, Wong, Oscar Gee-Wan, Masters, John R, Williamson, Magali
Format: Artigo
Idioma:Inglês
Publicat: BioMed Central 2012
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3317836/
https://ncbi.nlm.nih.gov/pubmed/22404908
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1476-4598-11-11
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