Effect of cancer-associated mutations in the PlexinB1 gene

BACKGROUND: Semaphorins act as chemotactic cues for cell movement via their transmembrane receptors, plexins. Somatic missense mutations in the plexinB1 gene coupled with overexpression of the protein frequently occur in prostate tumours, indicating a role for plexinB1 in the pathogenesis of prostat...

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Bibliografske podrobnosti
Main Authors: Zhou, Chun, Wong, Oscar Gee-Wan, Masters, John R, Williamson, Magali
Format: Artigo
Jezik:Inglês
Izdano: BioMed Central 2012
Teme:
Research
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3317836/
https://ncbi.nlm.nih.gov/pubmed/22404908
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1476-4598-11-11
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