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Rara haploinsufficiency modestly influences the phenotype of acute promyelocytic leukemia in mice
RARA (retinoic acid receptor alpha) haploinsufficiency is an invariable consequence of t(15;17)(q22;q21) translocations in acute promyelocytic leukemia (APL). Retinoids and RARA activity have been implicated in hematopoietic self-renewal and neutrophil maturation. We and others therefore predicted t...
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| Main Authors: | , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Society of Hematology
2011
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3317790/ https://ncbi.nlm.nih.gov/pubmed/21190992 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2010-08-300087 |
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