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The Effect of Osmolytes on Protein Fibrillation

Osmolytes are small molecules that are exploited by cells as a protective system against stress conditions. They favour compact protein states which makes them stabilize globular proteins in vitro and promote folding. Conversely, this preference for compact states promotes aggregation of unstructure...

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Detalles Bibliográficos
Main Authors: Macchi, Francesca, Eisenkolb, Maike, Kiefer, Hans, Otzen, Daniel E.
Formato: Artigo
Idioma:Inglês
Publicado: Molecular Diversity Preservation International (MDPI) 2012
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3317744/
https://ncbi.nlm.nih.gov/pubmed/22489184
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms13033801
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