The effects of hepatitis B virus integration into the genomes of hepatocellular carcinoma patients

Hepatitis B virus (HBV) infection is a leading risk factor for hepatocellular carcinoma (HCC). HBV integration into the host genome has been reported, but its scale, impact and contribution to HCC development is not clear. Here, we sequenced the tumor and nontumor genomes (>80× coverage) and tran...

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Detalhes bibliográficos
Main Authors: Jiang, Zhaoshi, Jhunjhunwala, Suchit, Liu, Jinfeng, Haverty, Peter M., Kennemer, Michael I., Guan, Yinghui, Lee, William, Carnevali, Paolo, Stinson, Jeremy, Johnson, Stephanie, Diao, Jingyu, Yeung, Stacy, Jubb, Adrian, Ye, Weilan, Wu, Thomas D., Kapadia, Sharookh B., de Sauvage, Frederic J., Gentleman, Robert C., Stern, Howard M., Seshagiri, Somasekar, Pant, Krishna P., Modrusan, Zora, Ballinger, Dennis G., Zhang, Zemin
Formato: Artigo
Idioma:Inglês
Publicado em: Cold Spring Harbor Laboratory Press 2012
Assuntos:
Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3317142/
https://ncbi.nlm.nih.gov/pubmed/22267523
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gr.133926.111
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