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Glutathione-dependent reductive stress triggers mitochondrial oxidation and cytotoxicity
To investigate the effects of the predominant nonprotein thiol, glutathione (GSH), on redox homeostasis, we employed complementary pharmacological and genetic strategies to determine the consequences of both loss- and gain-of-function GSH content in vitro. We monitored the redox events in the cytoso...
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| Main Authors: | , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Federation of American Societies for Experimental Biology
2012
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3316899/ https://ncbi.nlm.nih.gov/pubmed/22202674 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1096/fj.11-199869 |
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