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Temporal Patterns of Nucleotide Misincorporations and DNA Fragmentation in Ancient DNA

DNA that survives in museum specimens, bones and other tissues recovered by archaeologists is invariably fragmented and chemically modified. The extent to which such modifications accumulate over time is largely unknown but could potentially be used to differentiate between endogenous old DNA and pr...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Sawyer, Susanna, Krause, Johannes, Guschanski, Katerina, Savolainen, Vincent, Pääbo, Svante
Format: Artigo
Sprache:Inglês
Veröffentlicht: Public Library of Science 2012
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3316601/
https://ncbi.nlm.nih.gov/pubmed/22479540
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0034131
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