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Temporal Patterns of Nucleotide Misincorporations and DNA Fragmentation in Ancient DNA

DNA that survives in museum specimens, bones and other tissues recovered by archaeologists is invariably fragmented and chemically modified. The extent to which such modifications accumulate over time is largely unknown but could potentially be used to differentiate between endogenous old DNA and pr...

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Bibliografske podrobnosti
Main Authors: Sawyer, Susanna, Krause, Johannes, Guschanski, Katerina, Savolainen, Vincent, Pääbo, Svante
Format: Artigo
Jezik:Inglês
Izdano: Public Library of Science 2012
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3316601/
https://ncbi.nlm.nih.gov/pubmed/22479540
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0034131
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