Interactions between PPAR-α and inflammation-related cytokine genes on the development of Alzheimer’s disease, observed by the Epistasis Project

OBJECTIVE: Neuroinflammation contributes to the pathogenesis of sporadic Alzheimer’s disease (AD). Variations in genes relevant to inflammation may be candidate genes for AD risk. Whole-genome association studies have identified relevant new and known genes. Their combined effects do not explain 100...

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Hauptverfasser: Heun, Reinhard, Kölsch, Heike, Ibrahim-Verbaas, Carla A, Combarros, Onofre, Aulchenko, Yurii S, Breteler, Monique, Schuur, Maaike, van Duijn, Cornelia M, Hammond, Naomi, Belbin, Olivia, Cortina-Borja, Mario, Wilcock, Gordon K, Brown, Kristelle, Barber, Rachel, Kehoe, Patrick G, Coto, Eliecer, Alvarez, Victoria, Lehmann, Michael G, Deloukas, Panos, Mateo, Ignacio, Morgan, Kevin, Warden, Donald R, Smith, A David, Lehmann, Donald J
Format: Artigo
Sprache:Inglês
Veröffentlicht: e-Century Publishing Corporation 2012
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Original Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3316448/
https://ncbi.nlm.nih.gov/pubmed/22493750
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