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Replication by the Epistasis Project of the interaction between the genes for IL-6 and IL-10 in the risk of Alzheimer's disease

BACKGROUND: Chronic inflammation is a characteristic of Alzheimer's disease (AD). An interaction associated with the risk of AD has been reported between polymorphisms in the regulatory regions of the genes for the pro-inflammatory cytokine, interleukin-6 (IL-6, gene: IL6), and the anti-inflamm...

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Autores principales: Combarros, Onofre, van Duijn, Cornelia M, Hammond, Naomi, Belbin, Olivia, Arias-Vásquez, Alejandro, Cortina-Borja, Mario, Lehmann, Michael G, Aulchenko, Yurii S, Schuur, Maaike, Kölsch, Heike, Heun, Reinhard, Wilcock, Gordon K, Brown, Kristelle, Kehoe, Patrick G, Harrison, Rachel, Coto, Eliecer, Alvarez, Victoria, Deloukas, Panos, Mateo, Ignacio, Gwilliam, Rhian, Morgan, Kevin, Warden, Donald R, Smith, A David, Lehmann, Donald J
Formato: Artigo
Lenguaje:Inglês
Publicado: BioMed Central 2009
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC2744667/
https://ncbi.nlm.nih.gov/pubmed/19698145
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1742-2094-6-22
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