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Yos9p and Hrd1p mediate ER retention of misfolded proteins for ER-associated degradation

The endoplasmic reticulum (ER) has an elaborate quality control system, which retains misfolded proteins and targets them to ER-associated protein degradation (ERAD). To analyze sorting between ER retention and ER exit to the secretory pathway, we constructed fusion proteins containing both folded c...

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Autors principals: Izawa, Toshiaki, Nagai, Hiroyuki, Endo, Toshiya, Nishikawa, Shuh-ichi
Format: Artigo
Idioma:Inglês
Publicat: The American Society for Cell Biology 2012
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3315801/
https://ncbi.nlm.nih.gov/pubmed/22298424
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1091/mbc.E11-08-0722
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