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Quality control of nonstop membrane proteins at the ER membrane and in the cytosol
Since messenger RNAs without a stop codon (nonstop mRNAs) for organelle-targeted proteins and their translation products (nonstop proteins) generate clogged translocon channels as well as stalled ribosomes, cells have mechanisms to degrade nonstop mRNAs and nonstop proteins and to clear the transloc...
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| Udgivet i: | Sci Rep |
|---|---|
| Main Authors: | , , , , , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
Nature Publishing Group
2016
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4969602/ https://ncbi.nlm.nih.gov/pubmed/27481473 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep30795 |
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