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Promiscuous DNA synthesis by human DNA polymerase θ
The biological role of human DNA polymerase θ (POLQ) is not yet clearly defined, but it has been proposed to participate in several cellular processes based on its translesion synthesis capabilities. POLQ is a low-fidelity polymerase capable of efficient bypass of blocking lesions such as abasic sit...
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| Main Authors: | , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Oxford University Press
2012
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3315306/ https://ncbi.nlm.nih.gov/pubmed/22135286 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkr1102 |
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