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TDP-43 regulates global translational yield by splicing of exon junction complex component SKAR

TDP-43 is linked to neurodegenerative diseases including frontotemporal dementia and amyotrophic lateral sclerosis. Mostly localized in the nucleus, TDP-43 acts in conjunction with other ribonucleoproteins as a splicing co-factor. Several RNA targets of TDP-43 have been identified so far, but its ro...

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Detalhes bibliográficos
Main Authors: Fiesel, Fabienne C., Weber, Stephanie S., Supper, Jochen, Zell, Andreas, Kahle, Philipp J.
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2012
Assuntos:
RNA
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3315294/
https://ncbi.nlm.nih.gov/pubmed/22121224
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkr1082
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