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TDP-43 Overexpression Enhances Exon 7 Inclusion during the Survival of Motor Neuron Pre-mRNA Splicing

TDP-43 is a highly conserved, 43-kDa RNA-binding protein implicated to play a role in transcription repression, nuclear organization, and alternative splicing. More recently, this factor has been identified as the major disease protein of several neurodegenerative diseases, including frontotemporal...

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Detalhes bibliográficos
Main Authors: Bose, Jayarama Krishnan, Wang, I.-Fan, Hung, Li, Tarn, Woan-Yuh, Shen, C.-K. James
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2008
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2661999/
https://ncbi.nlm.nih.gov/pubmed/18703504
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M805376200
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