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Identification of an Intronic Splicing Enhancer Essential for the Inclusion of FGFR2 Exon IIIc

The ligand specificity of fibroblast growth factor receptor 2 (FGFR2) is determined by the alternative splicing of exons 8 (IIIb) or 9 (IIIc). Exon IIIb is included in epithelial cells, whereas exon IIIc is included in mesenchymal cells. Although a number of cis elements and trans factors have been...

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Detalles Bibliográficos
Main Authors: Seth, Puneet, Miller, Heather B., Lasda, Erika L., Pearson, James L., Garcia-Blanco, Mariano A.
Formato: Artigo
Idioma:Inglês
Publicado: American Society for Biochemistry and Molecular Biology 2008
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC2442303/
https://ncbi.nlm.nih.gov/pubmed/18256031
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M800087200
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