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Introns play an essential role in splicing-dependent formation of the exon junction complex
Pre-mRNA splicing specifically deposits the exon junction complex (EJC) onto spliced mRNA, which is important for downstream events. Here, we show that EJC components are primarily recruited to the spliceosome by association with the intron via the intron-binding protein, IBP160. This initial associ...
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| Main Authors: | , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
Cold Spring Harbor Laboratory Press
2007
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1948854/ https://ncbi.nlm.nih.gov/pubmed/17675447 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gad.1557907 |
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