Introns play an essential role in splicing-dependent formation of the exon junction complex

Pre-mRNA splicing specifically deposits the exon junction complex (EJC) onto spliced mRNA, which is important for downstream events. Here, we show that EJC components are primarily recruited to the spliceosome by association with the intron via the intron-binding protein, IBP160. This initial associ...

Full description

Saved in:
Bibliographic Details
Main Authors: Ideue, Takashi, Sasaki, Yasnory T.F., Hagiwara, Masatoshi, Hirose, Tetsuro
Format: Artigo
Language:Inglês
Published: Cold Spring Harbor Laboratory Press 2007
Subjects:
Research Communication
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC1948854/
https://ncbi.nlm.nih.gov/pubmed/17675447
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gad.1557907
Tags: Add Tag
No Tags, Be the first to tag this record!

Similar Items