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Splicing of U12-type introns deposits an exon junction complex competent to induce nonsense-mediated mRNA decay
Metazoan cells have two pathways for intron removal involving the U2- and U12-type spliceosomes, which contain mostly nonoverlapping sets of small nuclear ribonucleoproteins. We show that in vitro splicing of a U12-type intron assembles an exon junction complex (EJC) that is comparably positioned an...
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| Autores principales: | , , |
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| Formato: | Artigo |
| Lenguaje: | Inglês |
| Publicado: |
National Academy of Sciences
2004
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| Materias: | |
| Acceso en línea: | https://ncbi.nlm.nih.gov/pmc/articles/PMC539812/ https://ncbi.nlm.nih.gov/pubmed/15608055 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0408435102 |
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