Tissue-specific splicing regulator Fox-1 induces exon skipping by interfering E complex formation on the downstream intron of human F1γ gene

Fox-1 is a regulator of tissue-specific splicing, via binding to the element (U)GCAUG in mRNA precursors, in muscles and neuronal cells. Fox-1 can regulate splicing positively or negatively, most likely depending on where it binds relative to the regulated exon. In cases where the (U)GCAUG element l...

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Detalhes bibliográficos
Main Authors: Fukumura, Kazuhiro, Kato, Ayako, Jin, Yui, Ideue, Takashi, Hirose, Tetsuro, Kataoka, Naoyuki, Fujiwara, Toshinobu, Sakamoto, Hiroshi, Inoue, Kunio
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2007
Assuntos:
RNA
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2018636/
https://ncbi.nlm.nih.gov/pubmed/17686786
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkm569
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