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Evidence That the Kinase-Truncated c-Src Regulates NF-κB Signaling by Targeting NEMO
The tyrosine kinase c-Src and transcription factor NF-κB are considered crucial components required for normal osteoclastogenesis. Genetic ablation of either pathway leads to detrimental osteopetrotic phenotypes in mice. Similarly, obstruction of either pathway halts osteoclastogenesis and lessens v...
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| Main Authors: | , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2011
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3315184/ https://ncbi.nlm.nih.gov/pubmed/21538482 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/jcb.23170 |
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